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Michael B Bass Selected Research

motesanib diphosphate

11/2014A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours.
1/2014Challenges in developing a validated biomarker for angiogenesis inhibitors: the motesanib experience.
11/2010Biomarkers as predictors of response to treatment with motesanib in patients with progressive advanced thyroid cancer.
10/2010Phase 1 study of the investigational, oral angiogenesis inhibitor motesanib in Japanese patients with advanced solid tumors.
6/2007Safety, pharmacokinetics, and efficacy of AMG 706, an oral multikinase inhibitor, in patients with advanced solid tumors.

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Michael B Bass Research Topics

Disease

6Neoplasms (Cancer)
09/2016 - 03/2006
3Disease Progression
10/2014 - 06/2010
2Hypertension (High Blood Pressure)
11/2014 - 06/2014
2Fatigue
11/2014 - 06/2014
1Osteoarthritis
01/2019
1Pain (Aches)
01/2019
1Nausea
11/2014
1Constipation
11/2014
1Epistaxis (Nosebleed)
11/2014
1Vomiting
11/2014
1Dyspnea (Shortness of Breath)
10/2014
1Chest Pain (Chest Pains)
10/2014
1Pulmonary Embolism
10/2014
1Anemia
10/2014
1Hypokalemia
10/2014
1Neutropenia
10/2014
1Ovarian Neoplasms (Ovarian Cancer)
10/2014
1Diarrhea
06/2014
1Edema (Dropsy)
06/2014
1Exanthema (Rash)
06/2014
1Renal Cell Carcinoma (Grawitz Tumor)
06/2014
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2014
1Abdominal Pain (Pain, Abdominal)
12/2012
1Clear-cell metastatic renal cell carcinoma
12/2012
1Carcinoma (Carcinomatosis)
12/2012
1Osteosarcoma (Osteogenic Sarcoma)
12/2011
1medullary Thyroid cancer
11/2010
1Thyroid Neoplasms (Thyroid Cancer)
11/2010
1Urinary Bladder Neoplasms (Bladder Cancer)
06/2010

Drug/Important Bio-Agent (IBA)

5trebananibIBA
11/2014 - 06/2010
5motesanib diphosphateIBA
11/2014 - 06/2007
3Angiopoietin-1IBA
09/2016 - 06/2010
3Biomarkers (Surrogate Marker)IBA
01/2014 - 06/2010
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2014 - 06/2007
2TIE-2 Receptor (Receptor, TIE 2)IBA
09/2016 - 12/2012
2Sorafenib (BAY 43-9006)FDA Link
06/2014 - 12/2012
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
11/2010 - 10/2010
1Acetaminophen (Paracetamol)FDA LinkGeneric
01/2019
1Analgesics (Analgesic Drugs)IBA
01/2019
1Bevacizumab (Avastin)FDA Link
11/2014
1liposomal doxorubicin (Doxil)FDA Link
10/2014
11-dodecylpyridoxal (PLD)IBA
10/2014
1PlatinumIBA
10/2014
1Topotecan (Hycamtin)FDA LinkGeneric
10/2014
1Sunitinib (Sutent)FDA Link
06/2014
1Peptides (Polypeptides)IBA
12/2012
1Angiopoietin-2IBA
12/2012
1Dihydrotachysterol (AT 10)IBA
12/2012
1Epidermal Growth Factor (EGF)IBA
12/2012
1Immunoglobulins (Immunoglobulin)IBA
12/2012
1peptibody AIBA
12/2012
1ElementsIBA
12/2011
1Proteins (Proteins, Gene)FDA Link
12/2011
1Messenger RNA (mRNA)IBA
12/2011
1Angiogenesis InhibitorsIBA
10/2010
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
10/2010
1Docetaxel (Taxotere)FDA Link
06/2010
1Cisplatin (Platino)FDA LinkGeneric
06/2010
1GemcitabineFDA Link
06/2010
1Carboplatin (JM8)FDA LinkGeneric
06/2010
1Paclitaxel (Taxol)FDA LinkGeneric
06/2010
1Phosphotransferases (Kinase)IBA
06/2007
1AntibodiesIBA
03/2006
1Erythropoietin Receptors (Erythropoietin Receptor)IBA
03/2006

Therapy/Procedure

2Therapeutics
01/2014 - 11/2010
1Pain Management
01/2019
1Combined Modality Therapy
01/2019
1Drug Therapy (Chemotherapy)
06/2010